[Advances in Cancer Research] Volume 106 || CXC Chemokines in Cancer Angiogenesis and Metastases
β Scribed by Keeley, Ellen C.
- Book ID
- 120365500
- Publisher
- Elsevier
- Year
- 2010
- Weight
- 183 KB
- Category
- Article
- ISBN
- 0123747716
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Angiogenesis is attracting increased scientific and clinical interest. The identification of novel mediators and targeting molecules has led to significant progress in our understanding of tumor angiogenesis and tumor vessel targeting. Important advances in cancer treatment have already emerged, and
## Abstract Angiogenesis is essential for tumor growth and metastasis. Although ELR^+^βCXCβchemokines and their corresponding receptor, CXCβreceptor 2 (CXCR2), are known mediators of angiogenesis, little is known about their role in pancreatic cancer (PaCa). The aim of our study was to determine th