✦ LIBER ✦

[Advances in Cancer Research] Volume 105 || The Role of Clusterin (CLU) in Malignant Transformation and Drug Resistance in Breast Carcinomas

✍ Scribed by Redondo, Maximino

Book ID: 120063613
Publisher: Elsevier
Year: 2009
Tongue: English
Weight: 587 KB
Edition: 1
Category: Article
ISBN: 0123814294
DOI: 10.1016/S0065-230X(09)05002-7

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✦ Synopsis

The biological function of clusterin (CLU, also known as ApoJ, SGP2, TRPM2, CLI) has been puzzling researchers since its discovery and characterization in the early 1980s. Approaches such as cloning, expression and functional characterization of the different protein products generated by the CLU gene have now produced a critical mass of information of tremendous biological importance that are teaching us an important lesson in molecular biology of gene expression regulation. This volume brings together the contributions of top researchers in the field, providing an overview and synthesis of the latest thought and findings relating to CLU.

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