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Advanced glycosylation end products: A new disease marker for diabetes and aging

โœ Scribed by James T. Wu


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
339 KB
Volume
7
Category
Article
ISSN
0887-8013

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โœฆ Synopsis


Advanced glycosylation end products (AGEs) are a potentially useful marker for monitoring glycemic control, predicting the risk of diabetes-and aging-associated clinical complications, and monitoring the treatment of patients with micro-and macrovascular diseases, including retinopathy, atherosclerosis, nephropathy, and neuropathy. AGES or AGE-proteins are derived from nonenzymatically glycated proteins (Amadori products) after further cross-linking with other proteins and additional rearrangement. AGE-proteins can be assayed by either radioreceptor or immunoassays in blood and tissues. No commercial kit is available at this time.


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