Advanced glycosylation end products: A new disease marker for diabetes and aging
โ Scribed by James T. Wu
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 339 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0887-8013
No coin nor oath required. For personal study only.
โฆ Synopsis
Advanced glycosylation end products (AGEs) are a potentially useful marker for monitoring glycemic control, predicting the risk of diabetes-and aging-associated clinical complications, and monitoring the treatment of patients with micro-and macrovascular diseases, including retinopathy, atherosclerosis, nephropathy, and neuropathy. AGES or AGE-proteins are derived from nonenzymatically glycated proteins (Amadori products) after further cross-linking with other proteins and additional rearrangement. AGE-proteins can be assayed by either radioreceptor or immunoassays in blood and tissues. No commercial kit is available at this time.
๐ SIMILAR VOLUMES
## Objective: Osteoarthritis (oa) is one of the most prevalent and disabling chronic conditions affecting the elderly. its etiology is largely unknown, but age is the most prominent risk factor. the current study was designed to test whether accumulation of advanced glycation end products (ages), w
Background Advanced glycosylation end product (AGE) formation is a major mechanism for the development of complications in diabetes, and the possible roles of insulin-like growth factor 1 (IGF-1) and IGF binding protein 3 (IGFBP-3) are not clearly established. ## Methods We examined the associati
## Abstract ## Objective Receptor for advanced glycation end products (RAGE) serves as a pattern recognition receptor for several endogenous ligands that are potent inducers of inflammation. By activating endothelial cells and leukocytes, RAGE augments recruitment of leukocytes to sites of inflamm