Adult Wilms' tumor : A case report

✍ Scribed by Michele Orditura; Ferdinando De Vita; Giuseppe Catalano

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 370 KB
• Volume: 80
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/(sici)1097-0142(19971115)80:10<1961::aid-cncr13>3.0.co;2-w

✦ Synopsis

METHODS.

The authors describe a case of Wilms' tumor in a 23-year-old woman who developed hepatic and pulmonary metastases after undergoing nephrectomy.

Department of Internal and Experimental Medi-

Treatment was initiated with carboplatin, etoposide, ifosfamide, and epirubicin cine ''F. Magrassi'', Division of Medical Oncology, II University of Naples School of Medicine, combination chemotherapy and irradiation of the tumor bed, lungs, and liver. Naples, Italy.

RESULTS.

Metastatic workup was negative 41 months after suspension of chemoradiotherapy. Hematologic toxicity was high, but was manageable with adequate supportive care.

CONCLUSIONS.

Because this multimodal treatment, which included a chemotherapeutic regimen with single agents generally used in patients with recurrent disease, had impressive activity in this patient with an advanced adult Wilms' tumor, the issue of further investigation of this alternative schedule is raised.