✦ LIBER ✦

Adult T-cell leukemia-lymphoma unusual features of two patients from a low-incidence area

✍ Scribed by Judith J. Temple; Melissa G. Brammer; W. Abe Andes; Steve Covington; Setular Rangan

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 592 KB
Volume: 58
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19860801)58:3<694::aid-cncr2820580316>3.0.co;2-w

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✦ Synopsis

The occurrence of adult T-cell leukemia-lymphoma in two New Orleans patients, one native-born, the other originally from Honduras, is reported. Both exhibited an unusual feature. One patient was diagnosed following an atypical episode of sinusitis and demonstrated lymphomatous infiltration of the nasopharynx. A second patient had a fulminant course complicated by severe diarrhea and was found to have both tumor involvement and cytomegalovirus inclusions in the colon. Both had high titers of antibodies to HTLV-I. A cell line with T-lymphocyte characteristics was established from the peripheral blood of the first patient. Such studies may help better establish the clinical course, detection, and epidemiologic features of this difficult disease.

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