## Abstract Adult mesenchymal stem cells (MSCs) can be isolated from bone marrow or marrow aspirates and because they are cultureβdish adherent, they can be expanded in culture while maintaining their multipotency. The MSCs have been used in preclinical models for tissue engineering of bone, cartil
Adult stem cell plasticity: will engineered tissues be rejected?
β Scribed by Te-Chao Fang; Malcolm R. Alison; Nicholas A. Wright; Richard Poulsom
- Book ID
- 110756909
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 780 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0959-9673
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## Abstract ## Objective To determine whether it is possible to engineer 3βdimensional hyaline cartilage using mesenchymal stem cells derived from the bone marrow (BMSCs) of patients with osteoarthritis (OA). ## Methods Expanded BMSCs derived from patients with hip OA were seeded onto polyglycol