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Adult sporadic hypophosphatemic osteomalacia presenting as regional migratory osteoporosis

✍ Scribed by Jean-C. Gerster; Philippe Jaeger; Charles Gobelet; Georges Boivin


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
542 KB
Volume
29
Category
Article
ISSN
0004-3591

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✦ Synopsis


Osteoarticular manifestations associated with adult sporadic renal phosphate diabetes have previously been reported. We describe a 36-year-old man with phosphate diabetes who presented with migratory regional osteoporosis of the lower limbs. Our data suggest a cause-effect relationship between regional migratory osteoporosis and adult phosphate diabetes.

The osteoarticular manifestations which have been described in association with adult sporadic renal phosphate diabetes include osteomalacia (l), calcifications and ossifications in ligamentous and tendinous attachments (1-3), changes in sacroiliac joints and the spine that mimic ankylosing spondylitis (4), as well as necrosis of the femoral heads (5,6). As we show in this report., regional migratory osteoporosis of the lower limbs should be added to the list.

Case report. In August 1981, the patient, a 36-year-old man, noted onset of severe pain in the left knee 24 hours after a walk of 40 km, a distance which .______ From the Rheumatology and Rehabilitation Center, the