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Adult nonketotic hyperglycinemia (NKH) crisis presenting as severe chorea and encephalopathy

✍ Scribed by Deborah A. Hall; Steven P. Ringel


Book ID
102500138
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
446 KB
Volume
19
Category
Article
ISSN
0885-3185

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✦ Synopsis


We report on a patient with mild episodic nonketotic hyperglycinemia (NKH) on valproate who developed episodes of encephalopathy and chorea provoked by a fever and protein loading. After treatment with sodium benzoate and dextromethorphan, the patient's encephalopathy resolved and her chorea improved. The importance of this case is in recognizing this rare syndrome, which may present in the adult population.