Adult neurogenesis in Parkinson’s disease
✍ Scribed by Marxreiter, Franz; Regensburger, Martin; Winkler, Jürgen
- Book ID
- 120522358
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 635 KB
- Volume
- 70
- Category
- Article
- ISSN
- 1420-682X
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## Abstract We investigated the effects of exendin‐4 on neural stem/progenitor cells in the subventricular zone of the adult rodent brain and its functional effects in an animal model of Parkinson's disease. Our results showed expression of GLP‐1 receptor mRNA or protein in the subventricular zone
Adult neurogenesis occurs in the subgranular zone of the hippocampal dentate gyrus and the subventricular zone of the lateral ventricles. This process is highly regulated by intrinsic and extrinsic factors, which may control the proliferation and/or maturation of neural progenitor cells. Adult-born