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Adult gaucher disease in southern Tunisia: report of three cases

✍ Scribed by Faten Ben Rhouma; Faten Kallel; Rym Kefi; Wafa Cherif; Majdi Nagara; Hela Azaiez; Ines Jedidi; Moez Elloumi; Sonia Abdelhak; Sondes Mseddi


Book ID
115022987
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
226 KB
Volume
7
Category
Article
ISSN
1746-1596

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Adult Gaucher's disease (type I) is characterized by a deficiency of the catabolic lysosomal enzyme glucocerebrosidase that results in the accumulation of abnormal cells that contain glucocerebrosides in skeletal and reticuloendothelial tissues. Splenomegaly, hepatomegaly, anemia, thrombocytopenia,