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Adult and in utero exposure to cocaine alters sensitivity to the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

✍ Scribed by S.A. Lloyd; C.J. Faherty; R.J. Smeyne


Book ID
116787424
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
324 KB
Volume
137
Category
Article
ISSN
0306-4522

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1-methyl-4-phenyl-1,2,3,6-tetrahydropyri
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## Abstract We assessed the presence of degenerating neurons in the substantia nigra pars compacta (SNpc) and ventral tegmental area (VTA) of parkinsonian monkeys. For this purpose, we used two histological markers of cellular death, Fluoro Jade B (FJB) staining and terminal deoxynucleotidyl transf