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Adult acral cutaneous myofibromas in a patient with generalized morphea

โœ Scribed by Joseph C. English III; Amalie S. Derdeyn; Paula D. Smith; James W. Patterson

Book ID
117845489
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
960 KB
Volume
46
Category
Article
ISSN
1097-6787

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We report a 40-year-old patient with familial retinoblastoma also affecting his elder son, who developed multiple fibromas on the periungual or subungual areas of all the fingers. Molecular analysis disclosed a loss of heterozygosity for the RB1 gene in the larger tumour, with disappearance of the n