✦ LIBER ✦
Adsorption of antineoplastic drugs to polyalkylcyanoacrylate nanoparticles and their release in calf serum
✍ Scribed by P. Couvreur; B. Kante; M. Roland; P. Speiser
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 505 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
✦ Synopsis
Conditions are described for attaching anticancer drugs to polyalkylcyanoacrylate nanoparticles, a new drug delivery system for cells that exhibit endocytic uptake. They are ultrafine, metabolizable, and able to associate with various drugs in a nonspecific manner. Data are given for the in vitro degradation and for drug release from this new drug carrier system.