Adsorption, distribution and elimination of chloroquine in the presence of aspirin when administered into rabbits

Comparison of the developmental toxicity

Comparison of the developmental toxicity of aspirin in rabbits when administered throughout organogenesis or during sensitive windows of development

✍ G. D. Cappon; U. Gupta; J. C. Cook; M. S. Tassinari; M. E. Hurtt 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 98 KB 👁 2 views

## Abstract **BACKGROUND:** A review of the nonsteroidal anti‐inflammatory drug (NSAID) literature suggested occurrences of low‐level incidences of cardiovascular and midline defects in rabbit fetuses exposed in utero. Aspirin (acetylsalicylic acid, ASA) is a widely used NSAID that irreversibly inh