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ADrosophilamodel for the screening of bioavailable NADPH oxidase inhibitors and antioxidants

✍ Scribed by Nguyen Thi Tu Anh; Maiko Nishitani; Shigeharu Harada; Masamitsu Yamaguchi; Kaeko Kamei


Publisher
Springer
Year
2011
Tongue
English
Weight
872 KB
Volume
352
Category
Article
ISSN
0300-8177

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## Abstract ## Background Sustained hyperglycaemia induces increased renal oxygen consumption resulting in reduced oxygen availability in the diabetic kidney. We investigated the roles of the nicotinamide adenine dinucleotide phosphate (NADPH)‐oxidase and the neuronal nitric oxide synthase (nNOS)