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Adriamycin-induced DNA damage in human leukemia cells

✍ Scribed by Peter M. Kanter; Herbert S. Schwartz

Book ID
113237953
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
488 KB
Volume
3
Category
Article
ISSN
0145-2126

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## Abstract This study evaluated the potential cytotoxicity of the natural diterpenoids kauren‐19‐oic acid (KA), 14‐hydroxy‐kaurane (1) and xylopic acid (2), and semi‐synthetic derivatives of KA (3–5) towards human cancer cell lines (K562, HL60, MDA‐MB435 and SF295) and lymphocytes. Mouse erythrocy