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Adriamycin (14-hydroxydaunomycin), a novel antitumor antibiotic

✍ Scribed by F. Arcamone; G. Franceschi; S. Penco; A. Selva

Publisher
Elsevier Science
Year
1969
Tongue
French
Weight
184 KB
Volume
10
Category
Article
ISSN
0040-4039

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✦ Synopsis

We report herein the structural elucidation of adriamycin, an antitumor antibiotic which has been compared favourably with clinically useful daunoqyoin in the experimental chemotherapy studies. 1,* Adriamycin, C27H2YO11N, must have the same anthraquinone chromophore and glycoside structure as does daunomycin, 3 on the basic of spectroscopic data and of formation, on acid hydrolysis, of a red aglycone, adriamycinone, and of the aminosugar, daunosamine.

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