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Adrenomedullin induces heme oxygenase-1 gene expression and cGMP formation in rat vascular smooth muscle cells

โœ Scribed by Yong-Fen Qi; Lin-Wang Dong; Chun-Shui Pan; Jing Zhang; Bin Geng; Jing Zhao; Chao-Shu Tang

Book ID
116830705
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
182 KB
Volume
26
Category
Article
ISSN
0196-9781

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Oleanolic acid (OA), a widely used plant-derived triterpenoid, has been shown to possess potent antiatherosclerotic effects, which may be associated with the induction of heme oxygenase-1 (HO-1). However, the underlying mechanisms involved in the effect of OA on HO-1 expression are unclear. In the c