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Adrenal masses are associated with familial adenomatous polyposis

✍ Scribed by Thomas G. P. Johnson Smith; Susan K. Clark; David E. Katz; Rodney H. Reznek; Robin K. S. Phillips

Publisher
Springer
Year
2000
Tongue
English
Weight
451 KB
Volume
43
Category
Article
ISSN
0012-3706

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## Abstract The canonical Wnt pathway plays a key regulatory role in osteoblastogenesis and bone mass acquisition through its main effector, β‐catenin. Adenomatous polyposis coli (APC) represents the key intracellular gatekeeper of β‐catenin turnover, and heterozygous germ‐line mutations in the __A