Adrenal Function Following High-Dose Steroids in Ovarian Cancer Patients
โ Scribed by Giuseppe Del Priore; Karen J. Gurski; David P. Warshal; Cynthia Angel; Brent Dubeshter
- Book ID
- 115616668
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 166 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0090-8258
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The effects of oral MPA, 300 mg t.i.d., on adrenal function in postmenopausal patients with disseminated breast cancer were evaluated. The levels of serum cortisol, ACTH, androstenedione, DHEA-S, LH, FSH, GH, and prolactin in 22 patients receiving MPA were compared with those in another group of 28
To investigate the mechanism of adrenal suppression by high-dose MPA, we performed direct and indirect stimulation tests in postmenopausal women with disseminated breast cancer who were receiving MPA and in a postmenopausal breast cancer control group. A partial adrenal insufficiency was found durin