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Adrafinil-induced orofacial dyskinesia

✍ Scribed by Stéphane Thobois; Jing Xie; Helena Mollion; Isabelle Benatru; Emmanuel Broussolle

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
48 KB
Volume
19
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

We describe the first case of orofacial abnormal movements induced by adrafinil, a vigilance promoting agent of the same pharmacological class as modafinil. The dyskinesias did not spontaneously recover despite adrafinil withdrawal for a 4‐month period. They were secondly dramatically improved by tetrabenazine, a presynaptic dopaminergic depleting drug which was introduced after the 4‐month adrafinil‐free period. © 2004 Movement Disorder Society

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