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ADP mediates inhibition of insulin secretion by activation of P2Y13 receptors in mice

✍ Scribed by S. Amisten; S. Meidute-Abaraviciene; C. Tan; B. Olde; I. Lundquist; A. Salehi; D. Erlinge

Publisher
Springer
Year
2010
Tongue
English
Weight
221 KB
Volume
53
Category
Article
ISSN
0012-186X

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## Abstract Epidemiological and laboratory studies suggested that exposure to 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD) affects glucose homeostasis and increases the incidence of type 2 diabetes mellitus. To evaluate the effects of TCDD on insulin secretion from islets of Langerhans (islets),