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Adoptive transfer of antigen-specific T-cells of donor type for immunotherapy of viral infections following allogeneic hematopoietic cell transplants

✍ Scribed by Richard J. O’Reilly; Ekaterina Doubrovina; Deepa Trivedi; Aisha Hasan; Wouter Kollen; Guenther Koehne


Book ID
107572306
Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
283 KB
Volume
38
Category
Article
ISSN
0257-277X

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## Abstract The dynamics of CMV pp65 and IE‐1‐specific IFNγ‐producing CD8^+^ (IFNγ CD8^+^) and CD4^+^ (IFNγ CD4^+^) T cells and CMV DNAemia were assessed in 19 pre‐emptively treated episodes of active CMV infection. Peripheral counts of IFNγ CD8^+^ and IFNγ CD4^+^ T cells inversely correlated with