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Adoptive immunotherapy with genetically engineered T cells: modification of the IgG1 Fc ‘spacer’ domain in the extracellular moiety of chimeric antigen receptors avoids ‘off-target’ activation and unintended initiation of an innate immune response

✍ Scribed by Hombach, A; Hombach, A A; Abken, H


Book ID
109855493
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
590 KB
Volume
17
Category
Article
ISSN
0969-7128

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