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Adoptive immunotherapy is suppressed in C57BL/6J AND B6.C-H-2bm12 mice following recognition of congenic class II MHC antigen determinants

✍ Scribed by Robert Evans; Theodore M. Duffy


Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
589 KB
Volume
44
Category
Article
ISSN
0020-7136

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✦ Synopsis


All mice were injected with 200 mg CY/kg. After 6 hr, 50 X lo6 normal or immune spleen cells were injected intraveno~sly.-~14 days after CY or spleen-cell injection, mice were injected intradermally with MCN76-9 tumor cells. The resulting tumors were excised after 10 day~.-~Mice were challenged with an intramuscular injection of 2 X lo5 tumor cells. The number of mice with tumors was assessed 21 days later.