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Adoptive immunotherapy for cancer: building on success

✍ Scribed by Gattinoni, Luca; Powell, Daniel J.; Rosenberg, Steven A.; Restifo, Nicholas P.

Book ID: 109955376
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 859 KB
Volume: 6
Category: Article
ISSN: 1474-1741
DOI: 10.1038/nri1842

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## Background and Objectives: We evaluated the clinical efficacy of adoptive immunotherapy using in vitro activated cytotoxic T lymphocytes (CTL) in the treatment of patients with advanced cancer. Methods: CTL were induced with the mixed lymphocyte and tumor cell culture method, in which lymphocyte