Admission levels of serum Gc-globulin: Predictive value in fulminant hepatic failure

✍ Scribed by F V Schiødt; S Bondesen; I Petersen; K Dalhoff; P Ott; N Tygstrup

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 164 KB
• Volume: 23
• Category: Article
• ISSN: 0270-9139
• DOI: 10.1002/hep.510230409

✦ Synopsis

Gc-globulin scavenges actin released from necrotic he-the central nervous system with hepatic encephalopapatocytes to the extracellular space. In 77 patients with thy. 1

fulminant hepatic failure (FHF) (excluding patients

A major problem in the treatment of FHF is the decitreated with liver transplantation), admission levels of sion of orthotopic liver transplantation (OLTx). [2][3][4][5] Early serum Gc-globulin and degree of complexing with monoidentification of patients at risk of dying is essential meric actin (complex ratio) were determined to evaluate to avoid irreversible damages, primarily brain damage their predictive values in relation to survival/nonsurcaused by cerebral edema. Despite a number of studies vival. Gc-globulin levels were significantly reduced in 47 in this area, [6][7][8][9][10][11][12] reliable indicators of outcome in FHF nonsurvivors, compared with 30 survivors (96 { 71 mg/ are still not available. Prognostic indices may vary from L vs. 169 { 101 mg/L, P õ .001), whereas the complex center to center because of etiological differences or ratio in nonsurvivors did not differ significantly from that of survivors. Gc-globulin levels were significantly differences in the expression of apparent identical dislower in 59 patients with non-acetaminophen-induced eases.