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Administration of Vigabatrin (γ-Vinyl-γ-Aminobutyric Acid) Affects the Levels of Both Inhibitory and Excitatory Amino Acids in Rat Cerebrospinal Fluid

✍ Scribed by Toivo Halonen; Asla Pitkänen; Paavo J. Riekkinen

Book ID
111175843
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
548 KB
Volume
55
Category
Article
ISSN
0022-3042

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Inhibitory and excitatory amino acids in
Inhibitory and excitatory amino acids in CSF of patients suffering from complex partial seizures during chronic treatment with γ-vinyl GABA (vigabatrin)
✍ Toivo Halonen; Marjo Lehtinen; Asia Pitkänen; Aarne Ylinen; Paavo J. Riekkinen 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 799 KB

The effect of chronic administration of gamma-vinyl GABA (GVG; vigabatrin) on levels of neurotransmission-related amino compounds was studied in lumbar cerebrospinal fluid of 65 patients with complex partial epilepsy. The first sample of cerebrospinal fluid was taken before a 3-month period of treat