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Administration of prednisolone in vivo affects the ratio of OKT4OKT8 and the LDH-isoenzyme pattern of human T lymphocytes

โœ Scribed by R.J.M. ten Berge; H.P. Sauerwein; S.L. Yong; P.Th.A. Schellekens


Book ID
118374309
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
881 KB
Volume
30
Category
Article
ISSN
1090-2341

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Deletion and insertion mutations have been found to be a major component of the in vivo somatic mutation spectrum in the hypoxanthine phosphoribosyltransferase (hprt) gene of T-lymphocytes. In a population of 172 healthy people (average age, 34; mutant frequency, 10.3 x 10(-6)), deletion/insertion m