Administration of brain-derived neurotrophic factor suppresses the expression of heat shock protein 27 in rat retinal ganglion cells following axotomy
โ Scribed by A.M.R. Krueger-Naug; J.G. Emsley; T.L. Myers; R.W. Currie; D.B. Clarke
- Book ID
- 117490816
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 425 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0306-4522
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The administration of neurotrophins affects neuronal survival and growth, but less is known about their ability to modify the expression of growth associated genes following injury to CNS neurons. Here we characterize the effect of brain-derived neurotrophic factor (BDNF) on mRNA levels for Ta1 a-tu
Adult rat retinal ganglion cells (RGC) undergo degeneration after optic nerve transection. Studies have shown that exogenously applied neurotrophic factors such as brain-derived neurotrophic factor (BDNF) can attenuate axotomy-induced as well as developmental RGC death. Here, we examined whether gli