Patients with multiple cholesterol gallbladder stones have been found to be at a higher risk for the recurrence of gallstones after successful nonsurgical treatment than those with a solitary stone. Cholesterol gallstone recurrence, like primary gallstone formation, probably involves a triple defect
Administration of a terpene mixture inhibits cholesterol nucleation in bile from patients with cholesterol gallstones
✍ Scribed by Bergmann, K. ;Beck, A. ;Engel, C. ;Leiß, O.
- Publisher
- Springer-Verlag
- Year
- 1987
- Tongue
- English
- Weight
- 634 KB
- Volume
- 65
- Category
- Article
- ISSN
- 1432-1440
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tent forms with high crystallization rate in multiple cho-Besides classical plate-like cholesterol monohydrate lesterol stone patients. Tubules and spirals are transient crystals, a variety of crystal shapes have recently been forms that are associated with more extensive crystallidescribed in model
## I We investigated whether bile concentration influenced cholesterol saturation index or nucleation time of cholesterol monohydrate crystals in a large number of gallbladder bile samples. Pigment stone patients never had cholesterol crystals in their fresh biles, and nucleation time was always l
Gallbladder bile contains nucleation-promoting activity that binds to concanavalin A. The activity was found in gallbladder bile from cholesterol gallstone patients but also in gallbladder bile from patients without stones and patients with pigment stones. Bile from patients with multiple cholestero