Phase I, double-blind, randomized, place
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C. Janneke van der Woude; Pieter Stokkers; Ad A. van Bodegraven; Gert Van Assche
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Article
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2010
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John Wiley and Sons
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English
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๐ 2 views
Background: NI-0401 is a fully human monoclonal antibody, which binds to the CD3 subunit of the T-cell receptor, causing modulation of T-cell activity. We investigated the safety and the ability to modulate the TCR-CD3 complex of NI-0401 in patients with active Crohn's disease (CD). Methods: A doub