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ADMET for Medicinal Chemists (A Practical Guide) || Genetic Toxicity: In Vitro Approaches for Medicinal Chemists

โœ Scribed by Tsaioun, Katya; Kates, Steven A.

Book ID
120028962
Publisher
John Wiley & Sons, Inc.
Year
2010
Weight
289 KB
Category
Article
ISBN
0470484071

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The enormous cost incurred when a candidate drug fails in a clinical trial because of poor pharmacological parameters or severe side effects makes it imperative to screen for "safe" drugs in the very early stages of drug development. Various biochemical and other in vitro assays are thus used in con