Adjuvant therapy of triple negative breast cancer
β Scribed by Edith A. Perez; Alvaro Moreno-Aspitia; E. Aubrey Thompson; Cathy A. Andorfer
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 252 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0167-6806
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Combined modality trials in early breast cancer have been underway since the 1960s and results are available to indicate varying degrees of success in Stage I and 11. The trials have involved more than 29,000 women in 61 randomized trials. The recommendations can be summarized by stage, estrogen rec
About 180,000 American women will be diagnosed with early stage breast cancer during 1993. In many of these patients breast cancer is a systemic disease at diagnosis and thus not curable by local treatment alone. The development of optimal forms of systemic adjuvant therapy has been a major area of
## Background Triple-negative breast cancers (TNBC) neither express hormone receptors, nor overexpress HER2. They are associated with poor prognosis, as defined by low five-year survival and high recurrence rates after adjuvant therapy. Overall, TNBC share striking similarities with basal-like brea
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