Adjuvant multiple drug chemotherapy for osteosarcoma of the extremity
β Scribed by Dr. Charles Pratt; Ellen Shanks; Omar Hustu; Gaston Rivera; John Smith; A. P. Mahesh Kumar
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 609 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
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The side effects of chemotherapy on ovarian and reproductive functions in female patients who received adjuvant and/or neoadjuvant treatment for localized osteosarcoma of the extremities at our institution in the last 21 years (1974 -1995) were assessed. ## METHODS. Ninety-two patients with a mea
Twenty-nine patients with high-grade nonmetastatic osteogenic sarcoma of the extremities were treated with adjuvant chemotherapy following definitive surgery. Chemotherapy consisted of systemic intravenous Adriamycin and cisplatin in a sequential fashion given for six courses. Nineteen out of 29 pat
## Abstract ## BACKGROUND In primary central highβgrade osteosarcoma, a number of distinct subtypes have been identified, but little is known about the response to chemotherapy. ## METHODS The authors investigated whether the subtypes correlated with histologic response to chemotherapy in 1058 p