Adjuvant IL-15 does not enhance the efficacy of tumor cell lysate-pulsed dendritic cell vaccines for active immunotherapy of T cell lymphoma

Short-term dietary administration of cel

Short-term dietary administration of celecoxib enhances the efficacy of tumor lysate-pulsed dendritic cell vaccines in treating murine breast cancer

✍ Tobias Hahn; Irene Alvarez; James J. Kobie; Lalitha Ramanathapuram; Sharon Dial; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 910 KB

## Abstract Cyclooxygenase‐2 (COX‐2) is a rate‐limiting enzyme in the synthesis of prostaglandins. It is over‐expressed in multiple cancers and has been associated with diminished tumor immunity. Dendritic cells (DCs) are considered candidates for cancer immunotherapy due to their ability to proces