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Adjuvant effects of plasmid-generated hairpin RNA molecules on DNA vaccination

โœ Scribed by Dingfeng Li; Yong Liu; Yuwei Zhang; Jianqing Xu; Kunxue Hong; Maosheng Sun; Yiming Shao


Book ID
116959920
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
488 KB
Volume
25
Category
Article
ISSN
0264-410X

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## Abstract Because DNA vaccines on their own tend to induce weak immune responses in humans, adjuvant methods are needed in order to improve their efficacy. The coโ€stimulatory molecules 4โ€1BBL, OX40L, and CD70 have been shown to induce strong T cell activities; therefore, in this study, we investi