Adjuvant chemotherapy in Ewing's sarcoma
โ Scribed by Dr. S. H. Advani; D. N. Rao; K. A. Dinshaw; C. N. Nair; R. Gopal; J. J. Vyas; P. B. Desai
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 252 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0022-4790
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โฆ Synopsis
Adjuvant chemotherapy using vincristine, cyclophosphamide, and adriamycin was used in 28 patients with localized Ewing's sarcoma. Life-table analysis revealed 55% disease-free survival at 3 years. In contrast, our historical control showed less than 10% long-term survival. Adjuvant chemotherapy appears to control both micrometastasis as well as local residual disease. The present study demonstrates the improved survival with adjuvant chemotherapy including adriamycin, vincristine, and cyclophosphamide, in patients with localized Ewing's sarcoma.
๐ SIMILAR VOLUMES
Twenty-one patients with pathologically proven Ewing sarcoma without overt metastases at diagnosis were treated with a protocol designed by the Royal Marsden/St. Bartholomew's Hospitals Children's Solid Tumour Group (CSTG). They received megavoltage radiotherapy to the involved bone and adjuvant che
Between 1984Between -1987, 50 , 50 patients with Ewing's sarcoma of the bone were entered on combined modality protocol at Tata Memorial Hospital. Protocol treatment involved induction therapy consisting of 6-week therapy with vincristine, Adriamycin (doxorubicin), and cyclophosphamide (VDC) follow