Adjuvant chemotherapy and scar irradiation in breast cancer
✍ Scribed by Prof.; Dr. Fikri Içli; Dilek Dinçol; Erdoĝan Isikman; Muttalip Ünal
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 282 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
✦ Synopsis
Twenty-three consecutive premenopausal patients with breast cancer who had four or more positive axillary nodes were treated with six cycles of CMFP followed by irradiation limited to the mastectomy scar (CT-SRT). The relapse-free survival (RFS) rate was compared with a group of 15 patients who were treated with chemotherapy alone (CT). Following an average follow-up of 30 months, the relapse rates for the CT-SRT and CT groups were 30.4% vs. 73.2%, respectively (P<0.05).
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One hundred women with primary breast cancer with 4 or more metastatic axillary nodes were treated for 9 months postoperatively with vincristine, prednisone, cyclophosphamide, methotrexate, and fluorouracil (VPCMF). Sixty-five women have been observed for a minimum of 5 years or until failure and t
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