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Adjuvant aromatase inhibitor therapy for early breast cancer: A review of the most recent data

✍ Scribed by G. Grana


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
112 KB
Volume
93
Category
Article
ISSN
0022-4790

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✦ Synopsis


Abstract

Tamoxifen is the established adjuvant treatment for postmenopausal women with hormone‐sensitive early breast cancer. However, the side‐effects associated with tamoxifen therapy have prompted a search for safer and potentially more effective endocrine agents. Results from randomized trials of the third‐generation aromatase inhibitors, anastrozole, letrozole and exemestane, demonstrating improved efficacy compared with tamoxifen and favorable tolerability profiles, are discussed in this review. J. Surg. Oncol. 2006;93:585–592. © 2006 Wiley‐Liss, Inc.


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