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Adjuvant and protective properties of native and recombinant Bordetella pertussis adenylate cyclase toxin preparations in mice

โœ Scribed by Kalantar Hormozi; Roger Parton; John Coote

Book ID
114304481
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
253 KB
Volume
23
Category
Article
ISSN
0928-8244

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## Abstract The adenylate cyclase toxinโ€“hemolysin (ACT) is a key virulence factor of the whooping cough agent __Bordetella pertussis__ (__Bp__). The major cytotoxic activity of this 1706โ€residue protein consists of its capacity to invade a variety of eukaryotic cells directly across their cytoplasm