Adjuvant and neoadjuvant chemotherapy with dacarbazine in high-risk childhood melanoma
β Scribed by Arthur W. Boddie Jr.; Ayten Cangir
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 393 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0008-543X
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## Abstract ## BACKGROUND It has been shown that induction highβdose interferon Ξ±β2b (IFNβΞ±β2b) followed by maintenance therapy improves recurrenceβfree survival in adults with highβrisk, resected melanoma. In this study, the feasibility and toxicity of this regimen were evaluated in newly diagnos
## Background: Because the prognosis of patients with local-regional recurrence of melanoma treated with surgery alone usually is poor, the authors conducted a study designed to determine the efficacy of preoperative chemotherapy using cisplatin, vinblastine, and dacarbazine (cvd) in this patient p