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Adjusting for bias in C/E ratio estimates

✍ Scribed by Aaron A. Stinnett

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
216 KB
Volume
5
Category
Article
ISSN
1057-9230

No coin nor oath required. For personal study only.

✦ Synopsis

The estimator used to calculate incremental cost-effectiveness (C/E) ratios from sampled data is biased but consistent. While the bias may be negligible in studies with large sample sizes, it is potentially important in analyses based on small samples. When patient-level data on costs and effects are available, bootstrap simulation methods can be used to estimate the bias of a C/E ratio and adjust the point estimate accordingly.

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