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Adjunctive radiotherapy in the treatment of cutaneous squamous cell carcinoma with perineural invasion

✍ Scribed by Weston Waxweiler; Justin R. Sigmon; Daniel J. Sheehan

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 54 KB
Volume: 104
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.21810

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✦ Synopsis

Perineural invasion is a feature associated with significantly poorer outcomes when present in cutaneous squamous cell carcinoma (CSCC). The incidence of this subset of CSCC continues to rise in the US, as does the confusion surrounding exactly how it should be managed. While management typically involves excision, considerable debate exists as to the appropriate use of adjuvant radiotherapy (ART) in addition to excision. This article reviews the current relevant evidence for the use of ART.

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