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Adjunct Divalproex or Lithium to Clozapine in Treatment-Resistant Schizophrenia

✍ Scribed by Deanna L. Kelly; Robert R. Conley; Stephanie Feldman; Yang Yu; Robert P. McMahon; Charles M. Richardson


Publisher
Springer US
Year
2006
Tongue
English
Weight
352 KB
Volume
77
Category
Article
ISSN
0033-2720

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Reactive oxygen metabolites (ROM), produced by mononuclear phagocytes may participate in brain pathology. Clozapine (CLO) may modulate cell immunity, and it is also superior to conventional neuroleptics in conditions with a putative impact of oxidative damage by ROM, i.e. negative symptoms and neuro