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Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors

✍ Scribed by Constantin Jotzu; Eckhard Alt; Gabriel Welte; Jie Li; Bryan T. Hennessy; Eswaran Devarajan; Srinivasalu Krishnappa; Severin Pinilla; Lilly Droll; Yao-Hua Song

Book ID
107702457
Publisher
Springer Netherlands
Year
2011
Tongue
English
Weight
990 KB
Volume
34
Category
Article
ISSN
1570-5870

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## Abstract The purpose of this study is to test whether ectopic expression of Sox‐9 can induce adipose tissue‐derived stem cells (ASCs) to function as real nucleus pulposus (NP) cells in vitro. Adenoviral vectors expressing Sox‐9 were reported to infect the chondroblastic and human disc cells, whi