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Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells

✍ Scribed by Olorunseun Olatunji Ogunwobi; Ian L.P. Beales

Book ID
116857810
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
192 KB
Volume
134
Category
Article
ISSN
0167-0115

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## Abstract We previously demonstrated that leptin, an adipose‐derived hormone, induces cell proliferation in a model of preneoplastic (IMCE (__Apc__^Min/+^), but not normal (YAMC (__Apc__^+/+^), colon epithelial cells by inducing autocrine IL‐6 production and trans‐IL‐6 signaling. Low serum adipon