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Adiponectin reduces thermogenesis by inhibiting brown adipose tissue activation in mice

✍ Scribed by Qiao, Liping; Yoo, Hyung sun; Bosco, Chris; Lee, Bonggi; Feng, Gen-Sheng; Schaack, Jerome; Chi, Nai-Wen; Shao, Jianhua


Book ID
121549684
Publisher
Springer
Year
2014
Tongue
English
Weight
797 KB
Volume
57
Category
Article
ISSN
0012-186X

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beta3-Adrenergic-stimulated thermogenesis in brown adipose tissue (BAT) is diminished with age. beta3-Adrenergic receptors are positively coupled to adenylyl cyclase in BAT. To determine whether thermo- genesis, in response to direct activation of adenylyl cyclase, is also impaired with age, we exam