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Adiponectin receptors are downregulated in human gastric cancer

✍ Scribed by Kensuke Otani; Joji Kitayama; Takao Kamei; Daisuke Soma; Hideyo Miyato; Toshimasa Yamauchi; Takashi Kadowaki; Hirokazu Nagawa

Book ID: 106180649
Publisher: Springer Japan
Year: 2010
Tongue: English
Weight: 473 KB
Volume: 45
Category: Article
ISSN: 0944-1174
DOI: 10.1007/s00535-010-0228-2

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## Abstract Although obesity is a risk factor for colorectal cancer, the underlying mechanism is not clear. Adiponectin is an adipokine that binds to 2 types of receptors, AdipoR1 and AdipoR2. The plasma concentrations of adiponectin are reduced in obese individuals and adiponectin has been reporte