Adiponectin receptor 1 interacts with both subunits of protein kinase CK2
✍ Scribed by Cathleen Juhl; Karin Mörl; Annette G. Beck-Sickinger
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 303 KB
- Volume
- 356
- Category
- Article
- ISSN
- 0300-8177
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📜 SIMILAR VOLUMES
Protein kinase CK2 is a ubiquitous eukaryotic ser/thr protein kinase. The active holoenzyme is a heterotetrameric protein composed of catalytic (␣ and ␣Ј) and regulatory () subunits that phosphorylates many different protein substrates and appears to be involved in the regulation of cell division.
## Abstract The protein kinase CK2 is constituted by two catalytic (α and/or α′) and two regulatory (β) subunits. CK2 phosphorylates more than 300 proteins with important functions in the cell cycle. This study has looked at the relation between CK2 and p27^KIP1^, which is a regulator of the cell c